Resveratrol
Resveratrol is a powerful polyphenol linked to longevity, largely due to its activation of SIRT1 (a sirtuin enzyme), which is associated with aging and cellular health. By activating SIRT1, resveratrol supports mitochondrial function, enhances cellular resilience, and may reduce the impact of age-related damage. This activation promotes healthy metabolism, stress resistance, and longevity pathways, which can help extend healthspan – the period of life spent in good health. These effects make resveratrol a popular choice in supplements focused on promoting long-term vitality.
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Studies
24 -
Double blind placebo
Yes
References
- The effects of resveratrol on markers of oxidative stress in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled clinical trial
- Anti-inflammatory and antioxidant effects of resveratrol in healthy smokers a randomized, double-blind, placebo-controlled, cross-over trial
- A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease
- Resveratrol supplementation decreases blood glucose without changing the circulating CD14+CD16+ monocytes and inflammatory cytokines in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled study
- Six months of resveratrol supplementation has no measurable effect in type 2 diabetic patients. A randomized, double blind, placebo-controlled trial
- Effects of resveratrol on bone health in type 2 diabetic patients. A double-blind randomized-controlled trial